How many times a day should I apply aciclovir cream to a cold sore?
The NHS guidance suggests applying aciclovir cream to affected areas, such as cold sores, 5 times a day. It is important to wash hands before and after application.
✓ Accepted answer
You should apply aciclovir cream to a cold sore five times a day.
- Timing: In the UK, the NHS specifically advises applying the cream five times daily. This frequent schedule is designed to keep antiviral levels consistent to slow down the virus's replication.
- Duration: Continue treatment for the full two-week period, even if the sore heals sooner. Stopping early can allow the virus to persist and increase the risk of future outbreaks.
- Hygiene: Always wash your hands thoroughly before and after application. This prevents spreading the virus to other parts of your face or to other people.
- Application Technique: Use a clean cotton bud or your fingertip to apply a thin layer directly to the affected area and the skin immediately surrounding it.
- Early Intervention: For the best results, start the cream as soon as you notice the tingling or itching that precedes a blister. While the cream is available over the counter, US readers should note that prescription-only alternatives like topical penciclovir are also common.
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